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FRET hybridization probes. Among the different types of probes currently available in the market, the TaqMan probes are nowadays the probes of choice. The uorescence is determined cycle-bycycle by the RTi-PCR platform, and the result is an ampli cation plot. A typical ampli cation curve presents three different phases. The initiation phase occurs during the rst PCR cycles when the emitted uorescence cannot be distinguished from the baseline. During the exponential or log phase there is an exponential increase in uorescence, and nally, during the plateau phase, the reagents are exhausted, and no increase in uorescence is observed. Quanti cation is only possible, therefore, at the beginning of the exponential phase when the reaction is totally ef cient and all the reagents are available. The most important parameter in the RTi-PCR is the threshold cycle (CT value) (Higuchi et al. 1992), which is used for the quanti cation of the sample. It corresponds to the cycle at which a statistically signi cant increase in ampli cation-associated orescence is rst detected, and is inversely correlated to the concentration of DNA present in the original sample (Walker 2002). The initial DNA concentration of the sample can then be determined by interpolation of the resulting CT value in a linear standard curve of serially diluted, known-amount standards.

THREADID 10237338e99e7a8c STARRED Not Starred SENDER Ben Hammersley LABEL No Label SUBJECT This is the subject line DATE: Feb 21

Active Transaction A transaction that is running at the time of the failure. Before Commit State The state that a transaction enters just before it commits. Checkpoint The process of writing the logged completed transactions to the stable storage. Cold Backup A backup that is performed when there are no transactions running.

In fact, it is just about impossible to create a single client that would work with all the possible user devices, especially when smart phones are to be considered This was not a new issue, and the mobile device manufacturers are well aware of this problem, although differences across devices are exploited by the manufacturers themselves as they can be seen as unique selling points Within an experimental and innovation project such as MobiLife, however, this problem was directly linked with the issue of portability and introduced some limitations with regard to the devices that could be used While the use of Java technology, in principle, carries portability8 as an embedded feature, this principle often fails when mobile terminals, which constituted the target MobiLife user devices, are used.

Summers, J D, Rapoff, M A, Varghese, G, Porter, K, & Palmer, R E (1991) Psychosocial factors in chronic spinal cord injury pain Pain, 47, 183 189 Tota-Faucette, M E, Gil, K M, Williams, D A, Keefe, F J, & Goli, V (1993) Predictors of response to pain management treatment: The role of family environment and changes in cognitive processes Clinical Journal of Pain, 9, 115 123 Turk, D C (1990) Customizing treatment for chronic pain patients: Who, what, and why Clinical Journal of Pain, 6, 255 270 Turk, D C (1996) Biopsychosocial perspective on chronic pain In R J Gatchel & D C Turk (Eds), Psychological approaches to pain management: A practitioner s handbook (pp 3 30) New York: Guilford Press Turk, D C (1997) Psychological aspects of pain In P Bakule (Ed), Expert pain management (pp 124 178).

Springhouse, A: P Springhouse Turk, D C, & Flor, H (1999) Chronic pain: A biobehavioral perspective In R J Gatchel & D C Turk (Eds), Psychosocial factors in pain: Critical perspectives (pp 18 34) NewYork: Guilford Press Turk, D C, Meichenbaum, D, & Genest, M (1983) Pain and behavioral medicine: A cognitive-behavioral perspective New York: Guilford Press Turk, D C, & Melzack, R (1992) Handbook of pain assessment New York: Guilford Press Turk, D C, & Melzack, R (2001) Handbook of pain assessment (2nd ed) New York: Guilford Press Turk, D C, & Okifuji, A (1997) What factors affect physicians decisions to prescribe opioids for chronic non-cancer pain patients Clinical Journal of Pain, 13, 330 336 Turk, D C, & Okifuji, A (1998a) Ef cacy of multidisciplinary pain centers: An antidote for anecdotes Balliere s Clinical Anesthesiology, 12, 103 19.

1 Turk, D C, & Okifuji, A (1998b) Treatment of chronic pain patients: Clinical outcomes, cost-effectiveness and cost-bene ts of multidisciplinary pain centers Critical Reviews in Physical Medicine and Rehabilitation, 10, 181 208 Turk, D C, & Okifuji, A (1999) A cognitive-behavioral approach to pain management In P D Wall & R Melzack (Eds), Textbook of pain (4th ed, pp 1431 1445) NewYork: ChurchillLivingstone..

Dr. C received a doctorate in physics and was employed by a software company in a middle management position for 15 years. Dr. C became dissatisfied with his career choice and felt that he wanted to make a significant career change. He had been in psychotherapy for several years during and following his divorce and felt that becoming a therapist might be a satisfying career move. He enrolled in a local graduate program in psychology. Dr. C worked in several clinics during his graduate training. He introduced himself as Dr. C and had Dr. C printed on his business cards. Referring to himself as Dr. is misleading. His doctorate in physics is not relevant to his new career path, and potential clients are likely to believe that his doctorate is in psychology or a closely related field. Patients have a right to know exactly what service and provider they are paying for.